A woman (Melissa McCarthy) who wants a new life, wrecks her old car and loses her job at the local indigestible burger chain. Worse yet, at home she finds her husband (Nat Faxon) fooling around with a neighbor. Without money or a car, she complains to her alcoholic grandmother (Susan Sarandon), who wants to see Niagara Falls and together they make a new kind of Thelma and Louise. Also with Allison Janney, Toni Collette, Sandra Oh, Dan Aykroyd, Gary Cole and Kathy Bates. Directed by Ben Falcone and Melissa McCarthy. [1:36 . . .
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